Effective interpersonal and intergroup collaboration is essential for group and organizational performance. Moreover, groups and multi-team systems are flexible and versatile ways of organizing work and are used to perform a variety of tasks in modern organizations and society at large. The projects carried out by the research group explore the cognitive and affective dynamics associated with collaborative relationships. We argue that groups and multi-team systems are socio-cognitive and affective systems and we explore the way in which they integrate the cognitions and emotions of their members in order to generate solutions, to make decisions, to innovate or address complex societal issues (e.g., emergencies, rescue operations). We focus on interpersonal and intergroup relations as key dimensions that influence the emergence of system level properties (cognitions, emotions) that ultimately influence their performance. In terms of levels of analysis, we are interested in individual, group and multi-team system level antecedents and consequences of collaborative relationships. Through this comprehensive approach, in the context of collaborative relationships, we aim to gain insights on how individual, group and multi-team system functioning and effectiveness can be understood and improved.